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By Alton Meister

Advances in Enzymology and similar components of Molecular Biology is a seminal sequence within the box of biochemistry, providing researchers entry to authoritative reports of the newest discoveries in all components of enzymology and molecular biology. those landmark volumes date again to 1941, supplying an unequalled view of the historic improvement of enzymology. The sequence deals researchers the newest figuring out of enzymes, their mechanisms, reactions and evolution, roles in complicated organic method, and their program in either the laboratory and undefined. every one quantity within the sequence beneficial properties contributions via best pioneers and investigators within the box from around the globe. All articles are rigorously edited to make sure thoroughness, caliber, and clarity.

With its wide variety of themes and lengthy historic pedigree, Advances in Enzymology and comparable components of Molecular Biology can be utilized not just by means of scholars and researchers in molecular biology, biochemistry, and enzymology, but additionally by way of any scientist drawn to the invention of an enzyme, its houses, and its functions.


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5 . EN3 3 t 0 F L - R R - NH2 Various polyacrylamine derivatizations useful in the preparation of selective adsorbents for affinity chromatography (4,25). by the low porosity of these derivatives. This porosity is decreased further upon formation and reaction of the acyl azide step (4). D. LINKING OF PROTEINS TO AGAROSE The cyanogen bromide coupling procedures have been used t o covalently coupled various proteins t o agarose (4,22,23,64-82). Some specific and unique biochemical uses of such derivatives will be described in a later section.

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Van de Sande, J. , Nature, 227, 27 (1970). 11. Bumstead, R. , Dahl, J. , and Strominger, J. , J. Biol. , 243, 770 (1968). 12. Stewart, T. , Roberts, R. , and Strominger, J. , Nature, 230, 36 (1971). 13. Mandel, L. , Biochemistry, 2, 560 (1963). 14. I. , Biochem. Biophys. Res. ,36, 435 (1969). 15. , E’ed. , 24, 292 (1965). 16. Pillinger, D. , Hay, J . , Biochem. J . , 114, 429 (1969). 17. , Progr. in Nucleic Acid Res. and Mol. , l I , 391 (1971). 18. , and Boman, H. , Proc. N u t . Acacl. Sci.

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